Galerie Dominique Fiat develops a multitude of artistic practices in various mediums. Its transdisciplinary approach has allowed the discovery of a number of artists with multiple forms of expression, like Camille Henrot, Ed Moses and Ed Ruscha, as well as artists from the Light & Space movement, all of whom have gained international visibility. By taking an interest in non-Western scenes and particularly the MENASA scene from 2009, the Gallery exhibited Hicham Berrada at Palais de Tokyo, Paris and Villa Médicis, Rome, as well as Safâa Erruas, very early on. This initiation launched their international careers. Sue Williamson and Anita Dube are other artists who have exhibited at the gallery simultaneously with Centre Pompidou, Paris. In 2017, Dominique Fiat initiated and organised Afriques Capitales at the Grande Halle de la Villette.