Owusu-Ankomah studied fine arts at the Ghanatta College in Accra before moving to Germany. His distinctive paintings depict an alternate world wherein monumental human figures float and shift within an ocean of emblems that surround, support, and in fact, define them. The process by which these figures coexist and interact with various iconic and symbolic sets has developed through distinct phases over time, reflecting a personal journey of discovery. According to Owusu-Ankomah, ‘I am an artist who paints for humankind and who just happens to come from Africa.’

Owusu-Ankomah’s paintings have been exhibited on an international scale, touring Germany, the USA, the UK, Senegal, South Africa and Cuba. He has also collaborated with designer Giorgio Armani to develop a line of clothing for the Red Campaign, which raises awareness for the Global Fund to fight AIDS in Africa. His works are included in many important collections, including the British Museum in London, UK; the Hood Museum of Art in Hanover, USA; the Detroit Institute of Arts in Detroit, USA; and Renaissance Capital in Moscow, Russia.