Kwame Akoto ‘Almighty God’ showed an interest in painting from an early age and displayed obvious talent. Akoto‘s professional career began at fifteen with two local painters who taught him to paint billboards and decorate taxis and lorries. Akoto set up his own workshop in the mid-seventies in one of the most crowded and chaotic parts of Kumasi. In this same period Kwame Akoto embraced religion in the form of Christianity. He joined a Pentecostal sect known as the House of Faith Ministries and became a fervent preacher as well as a renowned healer. From then on Akoto began to call himself Almighty God, the name with which he signs all his works.
In the 1980s Akoto began to establish a name for himself in Europe. In 1991, his work was exhibited by Susan Vogel in the exhibition Africa Explores: 20th Century African Art, at the Center of African Art, New York. In 2006, he organized a large solo exhibition in Ghana at the Alliance Française, Accra. In addition, he participates in numerous group exhibitions in Europe and the United States.